Here are my nominations. I have so many picks, in fact, that I spent a lot of time narrowing it down to just the five shown below:
Four cylinders - Honda S2000 AP1: It may not have been an actual Type-R, but it definitely channeled their spirit. It redlined later than the AP2 (8800 vs. 8200 rpm), and still makes all of today’s affordable front-engined, rear drive sports cars - 86, BRZ and ND MX-5 all feel limp-wristed by comparison. Sadly, the chance of a replacement for the S2000 is almost nil, and even if it somehow came out, it’s unlikely that it would feel the same.
Six cylinders - Porsche 911 R (2016): I find this car to actually be even better-sounding than the previous-generation GT3 RS 4.0 (in my view, at least) - which was the very last road car ever to be powered by the iconic Mezger flat-six - and that’s saying something. It gets increasingly harder-edged as it approaches 8800 rpm. And when you consider that almost all of the current 911 range is turbocharged, that just makes the 911 R even more special, especially since unlike the dual-clutch-only GT3 RS with which it shares its engine, the R is available exclusively with a six-speed manual gearbox.
V8 - Ferrari 458 Speciale: There are plenty of great-sounding V8s, but for me, this one takes the cake, with a flat-plane crankshaft, 9000-rpm redline and a frenzied top-end shriek reminiscent of a 2.4-liter F1 car. We will most definitely never see or hear its like again.
V10 - Lexus LFA: It took 10 years to develop but all the expense was totally worth it, and like the Speciale, it also reminds me of old F1 cars (and sounds way better than the current crop of V6 turbo hybrids, too), although in this case it evokes memories from the earlier 3.0-liter and 3.5-liter eras. Again, it’s unlikely that any other car will sound as epic as this one does while it closes in on the rev limiter at 9500 rpm.
V12 - McLaren F1: evo Magazine once called it the best-sounding car in the world, and for good reason - its multifaceted growl throughout the rev range has never been bettered, let alone matched, and in all likelihood never will be. The hardcore LM and GTR long-tail versions, in particular, are just mind-bogglingly awesome.